2hnc

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Image:2hnc.png

Template:STRUCTURE 2hnc

Crystal structure of the human carbonic anhydrase II in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.

Template:ABSTRACT PUBMED 17000110

About this Structure

2HNC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfona mide to human isoform II. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6204-8. Epub 2006 Sep 26. PMID:17000110 doi:10.1016/j.bmcl.2006.09.022

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