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2zlf

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Image:2zlf.png

Template:STRUCTURE 2zlf

The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase

Template:ABSTRACT PUBMED 18610997

About this Structure

2ZLF is a 2 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Xu H, Fairman JW, Wijerathna SR, Kreischer NR, LaMacchia J, Helmbrecht E, Cooperman BS, Dealwis C. The structural basis for peptidomimetic inhibition of eukaryotic ribonucleotide reductase: a conformationally flexible pharmacophore. J Med Chem. 2008 Aug 14;51(15):4653-9. Epub 2008 Jul 9. PMID:18610997 doi:10.1021/jm800350u

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