3ehw

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Template:STRUCTURE 3ehw

Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site

Template:ABSTRACT PUBMED 8805593

About this Structure

3EHW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits., Mol CD, Harris JM, McIntosh EM, Tainer JA, Structure. 1996 Sep 15;4(9):1077-92. PMID:8805593

Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase., Varga B, Barabas O, Kovari J, Toth J, Hunyadi-Gulyas E, Klement E, Medzihradszky KF, Tolgyesi F, Fidy J, Vertessy BG, FEBS Lett. 2007 Oct 2;581(24):4783-8. Epub 2007 Sep 12. PMID:17880943

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