3bc4

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Template:STRUCTURE 3bc4

I84V HIV-1 protease in complex with a pyrrolidine diester

Template:ABSTRACT PUBMED 18720485

About this Structure

3BC4 is a 1 chain structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Bottcher J, Blum A, Dorr S, Heine A, Diederich WE, Klebe G. Targeting the open-flap conformation of HIV-1 protease with pyrrolidine-based inhibitors. ChemMedChem. 2008 Sep;3(9):1337-44. PMID:18720485 doi:10.1002/cmdc.200800113

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