3dt1

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Image:3dt1.png

Template:STRUCTURE 3dt1

P38 Complexed with a quinazoline inhibitor

Template:ABSTRACT PUBMED 18817365

About this Structure

3DT1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Herberich B, Cao GQ, Chakrabarti PP, Falsey JR, Pettus L, Rzasa RM, Reed AB, Reichelt A, Sham K, Thaman M, Wurz RP, Xu S, Zhang D, Hsieh F, Lee MR, Syed R, Li V, Grosfeld D, Plant MH, Henkle B, Sherman L, Middleton S, Wong LM, Tasker AS. Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold. J Med Chem. 2008 Sep 26. PMID:18817365 doi:10.1021/jm8005417

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