2w2q
From Proteopedia
PCSK9-DELTAC D374H MUTANT BOUND TO WT EGF-A OF LDLR
Template:ABSTRACT PUBMED 19001363
About this Structure
2W2Q is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural and biochemical characterization of the wild type PCSK9/EGF-AB complex and natural FH mutants., Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A, J Biol Chem. 2008 Nov 10. PMID:19001363
Page seeded by OCA on Wed Dec 24 11:00:30 2008
Categories: Homo sapiens | Baysarowich, J. | Bottomley, M J. | Calzetta, A. | Carfi, A. | Cirillo, A. | Cubbon, R M. | Cummings, R T. | Fisher, T S. | Francesco, R De. | Mattu, M. | Noto, A. | Orsatti, L. | Ruggeri, L. | Santoro, J C. | Sitlani, A. | Sparrow, C P. | Surdo, P Lo. | Talamo, F. | Cardiovascular disease | Egf | Familial hypercholesterolemia | Hydrolase | Hydrolase/receptor | Ldlr | Lipid metabolism | Lipid transport | Low-density lipoprotein receptor | Pcsk9 | Proprotein convertase | Receptor | Serine protease | Steroid metabolism