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3emg

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Image:3emg.png

Template:STRUCTURE 3emg

Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)

Template:ABSTRACT PUBMED 18938080

About this Structure

3EMG is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)., Farmer LJ, Bemis G, Britt SD, Cochran J, Connors M, Harrington EM, Hoock T, Markland W, Nanthakumar S, Taslimi P, Ter Haar E, Wang J, Zhaveri D, Salituro FG, Bioorg Med Chem Lett. 2008 Dec 1;18(23):6231-5. Epub 2008 Oct 7. PMID:18938080

Page seeded by OCA on Wed Dec 10 15:36:21 2008

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