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2zm1

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Revision as of 02:41, 30 January 2009 by OCA (Talk | contribs)
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Image:2zm1.png

Template:STRUCTURE 2zm1

Contents

Crystal structure of imidazo pyrazin 1 bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)

Template:ABSTRACT PUBMED 18977146

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

2ZM1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase., Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K, Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:18977146[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]

Page seeded by OCA on Wed Jan 28 20:32:25 2009

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