3eyh

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Template:STRUCTURE 3eyh

Crystal structures of JAK1 and JAK2 inhibitor complexes

Template:ABSTRACT PUBMED 19361440

About this Structure

3EYH is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Williams NK, Bamert RS, Patel O, Wang C, Walden PM, Wilks AF, Fantino E, Rossjohn J, Lucet IS. Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. J Mol Biol. 2009 Mar 20;387(1):219-32. Epub 2009 Jan 29. PMID:19361440 doi:http://dx.doi.org/10.1016/j.jmb.2009.01.041

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