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1xoy

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1xoy

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Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein

Overview

The structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of, the C-terminal domain of human thioredoxin-like protein, was determined by, NMR spectroscopy. The structure is dominated by a beta-barrel sandwich. A, two-stranded anti-parallel beta-sheet, which seals off one end of the, beta-barrel, is flanked by two flexible loops rich in acidic amino acids., Although this fold often provides a ligand binding site, the structure did, not reveal an appreciable cavity inside the beta-barrel. The, three-dimensional structure of At3g04780.1-des15 provides an entry point, for understanding its functional role and those of its mammalian homologs.

About this Structure

1XOY is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein., Song J, Tyler RC, Wrobel RL, Frederick RO, Vojtek FC, Jeon WB, Lee MS, Markley JL, Protein Sci. 2005 Apr;14(4):1059-63. Epub 2005 Mar 1. PMID:15741346

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