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2jc0

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Image:2jc0.png

Template:STRUCTURE 2jc0

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264

Template:ABSTRACT PUBMED 17269759

About this Structure

2JC0 is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Slater MJ, Amphlett EM, Andrews DM, Bravi G, Burton G, Cheasty AG, Corfield JA, Ellis MR, Fenwick RH, Fernandes S, Guidetti R, Haigh D, Hartley CD, Howes PD, Jackson DL, Jarvest RL, Lovegrove VL, Medhurst KJ, Parry NR, Price H, Shah P, Singh OM, Stocker R, Thommes P, Wilkinson C, Wonacott A. Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate. J Med Chem. 2007 Mar 8;50(5):897-900. Epub 2007 Feb 2. PMID:17269759 doi:10.1021/jm061207r

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