2pjy
From Proteopedia
Contents |
Structural basis for cooperative assembly of the TGF-beta signaling complex
Template:ABSTRACT PUBMED 18243111
Disease
Known disease associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[190230], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[190182], Esophageal cancer OMIM:[190182], Loeys-Dietz syndrome, type 1B OMIM:[190182], Loeys-Dietz syndrome, type 2B OMIM:[190182], Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this Structure
2PJY is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol Cell. 2008 Feb 1;29(2):157-68. PMID:18243111 doi:10.1016/j.molcel.2007.11.039
Page seeded by OCA on Wed Mar 17 08:56:08 2010