2i1r

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Template:STRUCTURE 2i1r

Contents 1 Novel Thiazolones as HCV NS5B Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex Structure 2 About this Structure 3 See Also 4 Reference

Novel Thiazolones as HCV NS5B Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex Structure

Template:ABSTRACT PUBMED 17049849

About this Structure

2i1r is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

See Also

• RNA polymerase

Reference

• Yan S, Larson G, Wu JZ, Appleby T, Ding Y, Hamatake R, Hong Z, Yao N. Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure. Bioorg Med Chem Lett. 2007 Jan 1;17(1):63-7. Epub 2006 Oct 4. PMID:17049849 doi:10.1016/j.bmcl.2006.09.095