1yy9
From Proteopedia
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Template:ABSTRACT PUBMED 15837620
About this Structure
1YY9 is a 3 chains structure with sequences from Homo sapiens and Mus musculus, homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Page seeded by OCA on Wed Mar 31 12:57:37 2010
Categories: Homo sapiens | Mus musculus, homo sapiens | Receptor protein-tyrosine kinase | Ferguson, K M. | Jeffrey, P D. | Kussie, P. | Li, S. | Schmitz, K R. | Wiltzius, J J.W. | Antigen:antibody complex | Antitumor | Cell surface receptor | Drug | Fab fragment | Glycoprotein | Immune system-transferase complex | Tyrosine kinase