1v7p

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Template:STRUCTURE 1v7p

Structure of EMS16-alpha2-I domain complex

Template:ABSTRACT PUBMED 15276841

About this Structure

1v7p is a 3 chain structure with sequence from Echis multisquamatus and Homo sapiens. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.

Reference

  • Horii K, Okuda D, Morita T, Mizuno H. Crystal structure of EMS16 in complex with the integrin alpha2-I domain. J Mol Biol. 2004 Aug 6;341(2):519-27. PMID:15276841 doi:10.1016/j.jmb.2004.06.036
  • Horii K, Okuda D, Morita T, Mizuno H. Structural characterization of EMS16, an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus. Biochemistry. 2003 Nov 4;42(43):12497-502. PMID:14580195 doi:10.1021/bi034890h
  • Emsley J, King SL, Bergelson JM, Liddington RC. Crystal structure of the I domain from integrin alpha2beta1. J Biol Chem. 1997 Nov 7;272(45):28512-7. PMID:9353312
  • Emsley J, Knight CG, Farndale RW, Barnes MJ, Liddington RC. Structural basis of collagen recognition by integrin alpha2beta1. Cell. 2000 Mar 31;101(1):47-56. PMID:10778855 doi:10.1016/S0092-8674(00)80622-4

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