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2i40

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Image:2i40.png

Template:STRUCTURE 2i40

Contents

Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor

Template:ABSTRACT PUBMED 16997559

About this Structure

2i40 is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Bamborough P, Christopher JA, Cutler GJ, Dickson MC, Mellor GW, Morey JV, Patel CB, Shewchuk LM. 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6236-40. Epub 2006 Sep 25. PMID:16997559 doi:10.1016/j.bmcl.2006.09.018

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OCA

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