5upj

From Proteopedia

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Template:STRUCTURE 5upj

Contents 1 HIV-2 PROTEASE/U99283 COMPLEX 2 About this Structure 3 See Also 4 Reference

HIV-2 PROTEASE/U99283 COMPLEX

Template:ABSTRACT PUBMED 7783120

About this Structure

5upj is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 2. Full crystallographic information is available from OCA.

See Also

• Virus protease

Reference

• Romines KR, Watenpaugh KD, Tomich PK, Howe WJ, Morris JK, Lovasz KD, Mulichak AM, Finzel BC, Lynn JC, Horng MM, et al.. Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors. J Med Chem. 1995 May 26;38(11):1884-91. PMID:7783120
• Skulnick HI, Johnson PD, Howe WJ, Tomich PK, Chong KT, Watenpaugh KD, Janakiraman MN, Dolak LA, McGrath JP, Lynn JC, et al.. Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors. J Med Chem. 1995 Dec 22;38(26):4968-71. PMID:8544171