1zhr

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Template:STRUCTURE 1zhr

Contents 1 Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Benzamidine (S434A-T475A-C482S-K437A Mutant) 2 About this Structure 3 See Also 4 Reference

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Benzamidine (S434A-T475A-C482S-K437A Mutant)

Template:ABSTRACT PUBMED 16204896

About this Structure

1zhr is a 1 chain structure of Factor XIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Factor XIa

Reference

• Jin L, Pandey P, Babine RE, Weaver DT, Abdel-Meguid SS, Strickler JE. Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors. Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1418-25. Epub 2005, Sep 28. PMID:16204896 doi:http://dx.doi.org/10.1107/S0907444905024340
• Navaneetham D, Jin L, Pandey P, Strickler JE, Babine RE, Abdel-Meguid SS, Walsh PN. Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2. J Biol Chem. 2005 Oct 28;280(43):36165-75. Epub 2005 Aug 6. PMID:16085935 doi:10.1074/jbc.M504990200