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1oj5

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Template:STRUCTURE 1oj5

CRYSTAL STRUCTURE OF THE NCO-A1 PAS-B DOMAIN BOUND TO THE STAT6 TRANSACTIVATION DOMAIN LXXLL MOTIF

Template:ABSTRACT PUBMED 14757047

About this Structure

1oj5 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Razeto A, Ramakrishnan V, Litterst CM, Giller K, Griesinger C, Carlomagno T, Lakomek N, Heimburg T, Lodrini M, Pfitzner E, Becker S. Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain. J Mol Biol. 2004 Feb 13;336(2):319-29. PMID:14757047
  • Litterst CM, Pfitzner E. An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1. J Biol Chem. 2002 Sep 27;277(39):36052-60. Epub 2002 Jul 22. PMID:12138096 doi:10.1074/jbc.M203556200
  • Litterst CM, Pfitzner E. Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. J Biol Chem. 2001 Dec 7;276(49):45713-21. PMID:11574547 doi:10.1074/jbc.M108132200

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