This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1sc9
From Proteopedia
Hydroxynitrile Lyase from Hevea brasiliensis in complex with the natural substrate acetone cyanohydrin
Template:ABSTRACT PUBMED 14998991
About this Structure
1sc9 is a 1 chain structure with sequence from Hevea brasiliensis. Full crystallographic information is available from OCA.
Reference
- Gruber K, Gartler G, Krammer B, Schwab H, Kratky C. Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236. J Biol Chem. 2004 May 7;279(19):20501-10. Epub 2004 Mar 3. PMID:14998991 doi:http://dx.doi.org/10.1074/jbc.M401575200
- Gruber K, Gugganig M, Wagner UG, Kratky C. Atomic resolution crystal structure of hydroxynitrile lyase from Hevea brasiliensis. Biol Chem. 1999 Jul-Aug;380(7-8):993-1000. PMID:10494852
- Zuegg J, Gruber K, Gugganig M, Wagner UG, Kratky C. Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Sci. 1999 Oct;8(10):1990-2000. PMID:10548044
- Wagner UG, Hasslacher M, Griengl H, Schwab H, Kratky C. Mechanism of cyanogenesis: the crystal structure of hydroxynitrile lyase from Hevea brasiliensis. Structure. 1996 Jul 15;4(7):811-22. PMID:8805565
