1tup

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Image:1tup.png

Template:STRUCTURE 1tup

TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA

Template:ABSTRACT PUBMED 8023157

About this Structure

1TUP is a 5 chains structure with sequences from Homo sapiens. The July 2002 RCSB PDB Molecule of the Month feature on p53 Tumor Suppressor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_7. Full crystallographic information is available from OCA.

Reference

  • Cho Y, Gorina S, Jeffrey PD, Pavletich NP. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 1994 Jul 15;265(5170):346-55. PMID:8023157

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