1t7i

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Template:STRUCTURE 1t7i

Contents 1 The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor. 2 About this Structure 3 See Also 4 Reference

The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.

Template:ABSTRACT PUBMED 15771427

About this Structure

1t7i is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

• Virus protease

Reference

• Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p