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1wbn

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Image:1wbn.png

Template:STRUCTURE 1wbn

Contents

FRAGMENT BASED P38 INHIBITORS

Template:ABSTRACT PUBMED 15658855

About this Structure

1wbn is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Gill AL, Frederickson M, Cleasby A, Woodhead SJ, Carr MG, Woodhead AJ, Walker MT, Congreve MS, Devine LA, Tisi D, O'Reilly M, Seavers LC, Davis DJ, Curry J, Anthony R, Padova A, Murray CW, Carr RA, Jhoti H. Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation. J Med Chem. 2005 Jan 27;48(2):414-26. PMID:15658855 doi:10.1021/jm049575n

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