3tgf

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Template:STRUCTURE 3tgf

Contents

THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA

Template:ABSTRACT PUBMED 2050136

Function

[TGFA_HUMAN] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

About this Structure

3tgf is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Harvey TS, Wilkinson AJ, Tappin MJ, Cooke RM, Campbell ID. The solution structure of human transforming growth factor alpha. Eur J Biochem. 1991 Jun 15;198(3):555-62. PMID:2050136

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