3g0x

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Image:3g0x.jpg

Template:STRUCTURE 3g0x

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5

Template:ABSTRACT PUBMED 19351152

About this Structure

3G0X is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t

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