3gcx

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Image:3gcx.png

Template:STRUCTURE 3gcx

Contents

PCSK9:EGFA (pH 7.4)

Template:ABSTRACT PUBMED 19224862

Disease

Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[606945]

About this Structure

3GCX is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem. 2009 Apr 17;284(16):10561-70. Epub 2009 Feb 17. PMID:19224862 doi:10.1074/jbc.M808802200

Page seeded by OCA on Wed Apr 29 20:55:57 2009

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