2zis

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Image:2zis.png

Template:STRUCTURE 2zis

Crystal Structure of rat protein farnesyltransferase complexed with a bezoruran inhibitor and FPP

Template:ABSTRACT PUBMED 19217288

About this Structure

2ZIS is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Asoh K, Kohchi M, Hyoudoh I, Ohtsuka T, Masubuchi M, Kawasaki K, Ebiike H, Shiratori Y, Fukami TA, Kondoh O, Tsukaguchi T, Ishii N, Aoki Y, Shimma N, Sakaitani M. Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1753-7. Epub 2009 Feb 11. PMID:19217288 doi:10.1016/j.bmcl.2009.01.074

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