3frz
From Proteopedia
Crystal Structure of HCV NS5B RNA polymerase in complex with PF868554
Template:ABSTRACT PUBMED 19209845
About this Structure
3FRZ is a Single protein structure of sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1 ,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-on e (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor., Li H, Tatlock J, Linton A, Gonzalez J, Jewell T, Patel L, Ludlum S, Drowns M, Rahavendran SV, Skor H, Hunter R, Shi ST, Herlihy KJ, Parge H, Hickey M, Yu X, Chau F, Nonomiya J, Lewis C, J Med Chem. 2009 Feb 11. PMID:19209845[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
Page seeded by OCA on Wed Mar 25 20:20:27 2009
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Single protein | Acetylation | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Cytoplasm | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Helicase | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transmembrane | Ubl conjugation | Viral nucleoprotein | Viral polymerase | Virion | Zinc
