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3gi3
From Proteopedia
Crystal structure of a N-Phenyl-N'-Naphthylurea analog in complex with p38 MAP kinase
Template:ABSTRACT PUBMED 19356929
About this Structure
3GI3 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cirillo PF, Hickey ER, Moss N, Breitfelder S, Betageri R, Fadra T, Gaenzler F, Gilmore T, Goldberg DR, Kamhi V, Kirrane T, Kroe RR, Madwed J, Moriak M, Netherton M, Pargellis CA, Patel UR, Qian KC, Sharma R, Sun S, Swinamer A, Torcellini C, Takahashi H, Tsang M, Xiong Z. Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors. Bioorg Med Chem Lett. 2009 May 1;19(9):2386-91. Epub 2009 Mar 26. PMID:19356929 doi:10.1016/j.bmcl.2009.03.104
Page seeded by OCA on Wed Oct 21 10:16:11 2009
Categories: Homo sapiens | Mitogen-activated protein kinase | Qian, K C. | Alternative splicing | Atp-binding | C-lobe alpha-helix | Cytoplasm | Kinase | N-lobe beta-sheet | Nucleotide-binding | Nucleus | Phosphoprotein | Polymorphism | Serine/threonine-protein kinase | Transferase | Two lobe kinase structure
