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3gpw

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Image:3gpw.jpg

Template:STRUCTURE 3gpw

Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand

Template:ABSTRACT PUBMED 19678642

About this Structure

3GPW is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x

Page seeded by OCA on Wed Sep 16 09:02:11 2009

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