Rebecca Martin/Sandbox1

From Proteopedia

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Template:STRUCTURE 3cm9

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Contents 1 Introduction 2 Dimeric and Secretory IgA 3 Secretory Component and Polyimmunoglobulin receptor 4 Insights into Function 5 Evolution 6 Implications in Science and Medicine 7 Limitations of the Current Studies 8 Questions for the Future 9 Links 9.1 IgA 9.2 Receptors 9.3 For Comparison 10 References

Introduction

Dimeric and Secretory IgA

Secretory Component and Polyimmunoglobulin receptor

spinqualitylabelsall models This is the secretory component. Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Insights into Function

Evolution

Implications in Science and Medicine

Limitations of the Current Studies

Questions for the Future

Links

IgA

• Model of human IgA2 determined by solution scattering, curve fitting and homology modelling 1r70
• Crystal structure of human FcaRI bound to IgA1-Fc 1ow0
• Solution structure of human dimeric immunoglobulin A 2qtj
• Solution structure of human secretory IgA1 3chn
• Solution Structure of Human SIgA2 3cm9
• Solution structure of human secretory component 2ocw

Receptors

• Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR 1XED
• Crystal structure of human FcaRI 10vz
• Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 2qej

For Comparison

• IgM: Solution structure of human Immunoglobulin M 2rcj
• IgG:
• IgD:
• IgE:

References