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3h0s

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Image:3h0s.jpg

Template:STRUCTURE 3h0s

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7

Template:ABSTRACT PUBMED 20219367

About this Structure

3H0S is a 3 chains structure with sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Corbett JW, Freeman-Cook KD, Elliott R, Vajdos F, Rajamohan F, Kohls D, Marr E, Zhang H, Tong L, Tu M, Murdande S, Doran SD, Houser JA, Song W, Jones CJ, Coffey SB, Buzon L, Minich ML, Dirico KJ, Tapley S, McPherson RK, Sugarman E, Harwood HJ Jr, Esler W. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2383-8. Epub 2009 Apr 24. PMID:20219367 doi:10.1016/j.bmcl.2009.04.091

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