3hdn

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Image:3hdn.jpg

Template:STRUCTURE 3hdn

Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2

Template:ABSTRACT PUBMED 19497745

About this Structure

3HDN is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hammond M, Washburn DG, Hoang HT, Manns S, Frazee JS, Nakamura H, Patterson JR, Trizna W, Wu C, Azzarano LM, Nagilla R, Nord M, Trejo R, Head MS, Zhao B, Smallwood AM, Hightower K, Laping NJ, Schnackenberg CG, Thompson SK. Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4441-5. Epub 2009 May 18. PMID:19497745 doi:10.1016/j.bmcl.2009.05.051

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