3eta
From Proteopedia
Contents |
Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor
Template:ABSTRACT PUBMED 19394223
About this Structure
3eta is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Patnaik S, Stevens KL, Gerding R, Deanda F, Shotwell JB, Tang J, Hamajima T, Nakamura H, Leesnitzer MA, Hassell AM, Shewchuck LM, Kumar R, Lei H, Chamberlain SD. Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3136-40. Epub 2009 Jan 6. PMID:19394223 doi:10.1016/j.bmcl.2008.12.110
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Chamberlain, S. | Deanda, F. | Gerding, R. | Hamajima, T. | Hassell, A. | Kumar, R. | Leesnitzer, A. | Lei, H. | Nakamura, H. | Patnaik, S. | Shewchuk, L. | Shotwell, B. | Stevens, K. | Tang, J. | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Receptor | Signaling protein | Transferase | Transmembrane | Tyrosine-protein kinase
