1evb

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Image:1evb.jpg

1evb

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Cyanobacterial toxin, phosphatase-1/-2A inhibitor, NMR

Overview

A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets.

About this Structure

1EVB is a Protein complex structure of sequences from Microcystis. Full crystallographic information is available from OCA.

Reference

Comparison of the solution structures of microcystin-LR and motuporin., Bagu JR, Sonnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF, Nat Struct Biol. 1995 Feb;2(2):114-6. PMID:7749913

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