2wl0

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Image:2wl0.jpg

Template:STRUCTURE 2wl0

HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY

Template:ABSTRACT PUBMED 19961222

About this Structure

2WL0 is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  • Mahalingam AK, Axelsson L, Ekegren JK, Wannberg J, Kihlstrom J, Unge T, Wallberg H, Samuelsson B, Larhed M, Hallberg A. HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J Med Chem. 2009 Dec 4. PMID:19961222 doi:10.1021/jm901165g

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