3hyf

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Template:STRUCTURE 3hyf

Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor

Template:ABSTRACT PUBMED 19791799

About this Structure

3HYF is a 1 chain structure of sequence from Escherichia coli, Human immunodeficiency virus 1 and Human immunodeficiency virus 1,escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Kirschberg TA, Balakrishnan M, Squires NH, Barnes T, Brendza KM, Chen X, Eisenberg EJ, Jin W, Kutty N, Leavitt S, Liclican A, Liu Q, Liu X, Mak J, Perry JK, Wang M, Watkins WJ, Lansdon EB. RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J Med Chem. 2009 Oct 8;52(19):5781-4. PMID:19791799 doi:10.1021/jm900597q

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