3f3v

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Image:3f3v.png

Template:STRUCTURE 3f3v

Kinase domain of cSrc in complex with inhibitor RL45 (Type II)

Template:ABSTRACT PUBMED 19462975

About this Structure

3F3V is a 2 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928

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