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3i08

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Template:STRUCTURE 3i08

Crystal structure of the S1-cleaved Notch1 Negative Regulatory Region (NRR)

Template:ABSTRACT PUBMED 19701457

About this Structure

3i08 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gordon WR, Vardar-Ulu D, L'Heureux S, Ashworth T, Malecki MJ, Sanchez-Irizarry C, McArthur DG, Histen G, Mitchell JL, Aster JC, Blacklow SC. Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2. PLoS One. 2009 Aug 24;4(8):e6613. PMID:19701457 doi:10.1371/journal.pone.0006613

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