2knv

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Image:2knv.jpg

Template:STRUCTURE 2knv

Contents

NMR dimer structure of the UBA domain of p62 (SQSTM1)

Template:ABSTRACT PUBMED 19931284

Disease

Known disease associated with this structure: Paget disease of bone OMIM:[601530]

About this Structure

2KNV is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Long J, Garner TP, Pandya MJ, Craven CJ, Chen P, Shaw B, Williamson MP, Layfield R, Searle MS. Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling. J Mol Biol. 2010 Feb 12;396(1):178-94. Epub 2009 Nov 17. PMID:19931284 doi:10.1016/j.jmb.2009.11.032

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