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3hhm
From Proteopedia
Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin
Disease
Known disease associated with this structure: Breast cancer, somatic OMIM:[171834], Colorectal cancer, somatic OMIM:[171834], Gastric cancer, somatic OMIM:[171834], Hepatocellular carcinoma, somatic OMIM:[171834], Keratosis, seborrheic, somatic OMIM:[171834], Nevus, epidermal OMIM:[171834], Nonsmall cell lung cancer, somatic OMIM:[171834], Ovarian cancer, somatic OMIM:[171834]
About this Structure
3HHM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Sep 30 09:28:29 2009
Categories: Homo sapiens | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Amzel, L M. | Gabelli, S B. | Mandelker, D. | Vogelstein, B. | 5-triphosphate | Atp-binding | Disease mutation | H1047r | Kinase | Nucleotide-binding | Oncogene | P110 | P85 | Phosphatidilynositol 3 | Pi3k | Pi3kca | Pik3r1 | Polymorphism | Transferase | Transferase/oncoprotein complex | Wortmannin
