3idp
From Proteopedia
B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
Template:ABSTRACT PUBMED 19764794
About this Structure
3IDP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g
Page seeded by OCA on Wed Oct 7 13:56:38 2009
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Epstein, L F. | Whittington, D A. | Acetylation | Atp-binding | Cardiomyopathy | Cytoplasm | Dfg-out | Disease mutation | Kinase | Metal-binding | Nucleotide-binding | Oncogene | Phorbol-ester binding | Phosphoprotein | Polymorphism | Proto-oncogene | Serine/threonine-protein kinase | Transferase | Zinc | Zinc-finger
