3ii5

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Image:3ii5.jpg

Template:STRUCTURE 3ii5

The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor

Template:ABSTRACT PUBMED 19864136

About this Structure

3II5 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. Epub 2009 Oct 26. PMID:19864136 doi:10.1016/j.bmcl.2009.10.049

Page seeded by OCA on Wed Nov 11 22:29:42 2009

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