User:Karl Oberholser/Sandbox 1

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Syn and Anti Configurations of Nucleosides and Nucleotides

Detailed description of nucleosides and nucleotides.

Purine Nucleosides

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Observe that the adenine ring of adenosine is nearly perpendicular to the furanose ring and that a (colored green) connects adenine to ribofuranose. Groups on the ribofuranose, such as the on the 2' carbon sterically hinder the rotation of the adenine about the glycosidic bond. This lack of ability to rotate results in two possible configurations. The anti configuration, which you have been viewing, but now in and the , , same view but in .

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Karl Oberholser

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