1hxw

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Image:1hxw.png

Template:STRUCTURE 1hxw

HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538

Template:ABSTRACT PUBMED 7708670

About this Structure

1HXW is a 2 chains structure of sequences from Human immunodeficiency virus 1. The June 2000 RCSB PDB Molecule of the Month feature on HIV-1 Protease by David S. Goodsell is 10.2210/rcsb_pdb/mom_2000_6. Full crystallographic information is available from OCA.

Reference

  • Kempf DJ, Marsh KC, Denissen JF, McDonald E, Vasavanonda S, Flentge CA, Green BE, Fino L, Park CH, Kong XP, et al.. ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2484-8. PMID:7708670

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