2f8s

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Image:2f8s.png

Template:STRUCTURE 2f8s

Crystal structure of Aa-Ago with externally-bound siRNA

Template:ABSTRACT PUBMED 17027504

About this Structure

2F8S is a 4 chains structure of sequences from Aquifex aeolicus. The February 2008 RCSB PDB Molecule of the Month feature on Small Interfering RNA by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_2. Full crystallographic information is available from OCA.

Reference

  • Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA. Structure. 2006 Oct;14(10):1557-65. PMID:17027504 doi:http://dx.doi.org/10.1016/j.str.2006.08.009

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