3e4z

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Template:STRUCTURE 3e4z

Contents 1 Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II 2 Disease 3 About this Structure 4 Reference

Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II

Template:ABSTRACT PUBMED 19896952

Disease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147470]

About this Structure

3E4Z is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

Page seeded by OCA on Wed Dec 9 14:02:12 2009