1cwl

From Proteopedia

Revision as of 13:55, 5 November 2007 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1cwl.gif

1cwl, resolution 1.80Å

Drag the structure with the mouse to rotate

HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN

Overview

Eight new X-ray structures of different cyclophilin, A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide, a useful structural database for the analysis of protein-ligand, interactions. The effect of small chemical differences on protein-ligand, hydrogen-bonding, van der Waals interactions and water structure is, presented.

About this Structure

1CWL is a Single protein structure of sequence from Homo sapiens. Active as Peptidylprolyl isomerase, with EC number 5.2.1.8 Structure known Active Site: BIN. Full crystallographic information is available from OCA.

Reference

X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:9769216

Page seeded by OCA on Mon Nov 5 16:00:28 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cwl"
Personal tools