Copper, Zinc Superoxide Dismutase

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Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.

Contents 1 Cu/Zn Superoxide Dismutase 2 Introduction 3 The Reaction of Dismutase 4 General Structure

Cu/Zn Superoxide Dismutase

Cu/Zn Superoxide (SODc) dismutase is an oxidoreductase enzyme, catalyzing the dismutation of superoxide into oxygen and hydrogen peroxide.

Introduction

Cu/Zn Superoxide dismutase is an important antioxidant defense in nearly all cells exposed to oxygen.

Cu2+ Zn Superoxide Dismutase belongs to the superfamily of oxidoreductases, specifically those acting on superoxide as acceptor.

The Reaction of Dismutase

General Structure

Cu/Zn Superoxide dismutase contains four polypeptide chains (B,O,G,Y). Each chain contains one alpha-helix and 12-14 beta-sheets.