SecA

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Introduction

The SecA The ATPase SecA drives the post-translational translocation of proteins through the SecY channel in the bacterial inner membrane. SecA is a dimer that can dissociate into monomers under certain conditions. Many bacterial proteins are transported post-translationally across the inner membrane by the Sec machinery, which consists of two essential components (1-4). One is the SecY complex, which forms a conserved heterotrimeric protein-conducting channel in the inner membrane (5, 6). The other is SecA, a cytoplasmic ATPase, which "pushes" substrate polypeptide chains through the SecY channel (7). http://journal.shouxi.net/qikan/article.php?id=418668




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